Iridium-Catalyzed Diastereo- and Enantioselective [4 + 1] Cycloaddition of Hydroxyallyl Anilines with Sulfoxonium Ylides
Chunlan He, Yaping Tang, Shengbiao Tang and Jiangtao Sun*
*Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China,
Email: jtsun
cczu.edu.cn
C. He, Y. Tang, S. Tang, J. Sun, Org. Lett., 2023, 25, 4621-4626.
DOI: 10.1021/acs.orglett.3c01217
see article for more reactions
Abstract
An iridium-catalyzed diastereo- and enantioselective [4 + 1] cycloaddition reaction of hydroxyallyl anilines with sulfoxonium ylides provides 3-vinyl indolines in good yields with excellent enantioselectivities under mild reaction conditions.
see article for more examples
proposed mechanism
Key Words
ID: J54-Y2023
