Ligand-Free Palladium-Catalyzed Substoichiometric Base Mediated Carbonylation of Aryl Iodides with Alkenylboronic Acids under Ambient Conditions
Lili Tang, Yanqun Gao, Junjie Chen, Linlin Yang, Bing Xiao, Ge Shen, Yuejun Ouyang*, Wei Han*
*Huaihua University, Huaihua 418008; Nanjing Normal University, Wenyuan Road No.1, Nanjing 210023, P. R. of China, Email:
oyyj0816
163.com, hanweinjnu.edu.cn
L. Tang, Y. Gao, J. Chen, L. Yang, B. Xiao, G. Shen, Y. Ouyang, W. Han, Synlett, 2023, 34, 1280-1284.
DOI: 10.1055/a-2007-2958
Abstract
A highly efficient, practical, and ligand-free palladium-catalyzed carbonylation of aryl iodides with alkenylboronic acids provides a variety of chalcones and α-branched enones in good yields under an ambient pressure of CO at room temperature. Moreover, the transformation proceeds well in the presence of a substoichiometric amount of base.
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Key Words
palladium catalysis, carbonylation, aryl iodides, alkenylboronic acids, chalcones, enones
ID: J72-Y2023
