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Visible-Light-Promoted Click [3+2] Cycloaddition of Aziridine with Alkyne: An Efficient Synthesis of Dihydropyrrolidine

Ritu Kapoor, Ruchi Chawla, Ankit Verma, Twinkle Keshari, I. R. Siddiqui*

*Department of Chemistry, University of Allahabad, Prayagraj 211002, India, Email:

R. Kapoor, R. Chawla, A. Verma, T. Keshari, I. R. Siddiqui, Synlett, 2023, 34, 1621-1625.

DOI: 10.1055/a-2099-6309

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A photocatalytic [3+2] cycloaddition of aziridines with activated alkynes provides polysubstituted pyrrolidines in good yields under visible-light irradiation in the presence of ruthenium catalyst. This  cyclocarboamination combines energy transfer and redox neutral reactions in a photocascade reaction.

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Key Words

aziridines, alkynes, 2-pyrrolines, visible light, click chemistry, photoredox catalysis, photochemistry

ID: J72-Y2023