Visible-Light-Promoted Click [3+2] Cycloaddition of Aziridine with Alkyne: An Efficient Synthesis of Dihydropyrrolidine
Ritu Kapoor, Ruchi Chawla, Ankit Verma, Twinkle Keshari, I. R. Siddiqui*
*Department of Chemistry, University of Allahabad, Prayagraj 211002, India,
Email: irsiddiqui
gmail.com
R. Kapoor, R. Chawla, A. Verma, T. Keshari, I. R. Siddiqui, Synlett, 2023, 34, 1621-1625.
DOI: 10.1055/a-2099-6309
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Abstract
A photocatalytic [3+2] cycloaddition of aziridines with activated alkynes provides polysubstituted pyrrolidines in good yields under visible-light irradiation in the presence of ruthenium catalyst. This cyclocarboamination combines energy transfer and redox neutral reactions in a photocascade reaction.
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Key Words
aziridines, alkynes, 2-pyrrolines, visible light, click chemistry, photoredox catalysis, photochemistry
ID: J72-Y2023
