Strain-Inducing Positional Alkene Isomerization
Vignesh Palani and Alison E. Wendlandt*
*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States,
Email: awendlan
mit.edu
V. Palani, A. E. Wendlandt, J. Am. Chem. Soc., 2023, 145, 20053-20061.
DOI: 10.1021/jacs.3c06935
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Abstract
A strain-inducing positional alkene isomerization reaction provides mild and selective access to cyclobutene building blocks from readily obtained cyclobutylidene precursors. This endergonic isomerization relies on the sequential and synergistic action of a decatungstate polyanion photocatalyst and cobaloxime co-catalyst to store potential energy in the form of ring strain.
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proposed reaction pathway
Key Words
cyclobutenes, isomerizations of alkenes, photochemistry
ID: J48-Y2023
