Transsulfinamidation of Sulfinamides with Amines
Saori Tsuzuki and Taichi Kano*
*Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan,
Email: kano
go.tuat.ac.jp
S. Tsuzuki, T. Kano, Org. Lett., 2023, 25, 6677-6681.
DOI: 10.1021/acs.orglett.3c02534
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Abstract
Metal- and additive-free transsulfinamidations of N-unsubstituted sulfinamides and N-pivaloyl-protected sulfinamides with various amines provide both N-monosubstituted and N,N-disubstituted sulfinamides in good yields simply by heating. Preliminary experiments also indicate that alcohols can be used as nucleophiles too.
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Key Words
ID: J54-Y2023
