Electrochemical Oxidative Carbonylation of NH-Sulfoximines
Mingzhe Li, Mengyu Peng, Wenxiu Huang, Longqiang Zhao, Shoucai Wang, Chen Kang, Guangbin Jiang* and Fanghua Ji*
*College of Chemistry and Bio-engineering, Guilin University
of Technology, 12 Jiangan Road, Guilin 541004, China, Email: jianggb
glut.edu.cn,
fanghuajiglut.edu.cn
M. Li, M. Peng, W. Huang, L. Zhao, S. Wang, C. Kang, G. Jiang, F. Ji, Org. Lett., 2023, 25, 7529-7534.
DOI: 10.1021/acs.orglett.3c02800
Abstract
An electrochemical, Pd-catalyzed N-aroylation of NH-sulfoximines with arylhydrazine hydrochlorides and carbon monoxide in the presence of TBAI provides a wide range of products in good yield. This oxidant- and ligand-free method offers mild reaction conditions that are easy to scale up to gram scale.
see article for more examples
proposed mechanism
Key Words
sulfoximines, electrochemistry, multicomponent reactions
ID: J54-Y2023
