Chemo-, Regio-, and Stereoselective Access to (E)-Boryl-Substituted Allyl Fluorides via Electrophilic Fluorodesilylation
Yongsuk Jung, Seung Hwan Cho*
*Department of Chemistry, Pohang University of Science and
Technology (POSTECH), Pohang, 37673, Republic of Korea, Email: seunghwan
postech.ac.kr
Y. Jung, S. H. Cho, Synlett, 2023, 34, 2165-2168.
DOI: 10.1055/a-2089-4260
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Abstract
A transition-metal-free chemo-, regio-, and stereoselective electrophilic fluorodesilylation of α-silyl-substituted allylboronate esters with Selectfluor provides a variety of (E)-boryl-substituted allyl fluorides in good yields. Further modifications of the obtained (E)-boryl-substituted allyl fluorides afford allyl or alkyl fluoride derivatives.
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Key Words
allyl fluorides, fluorodesilylation, vinylboronates, Selectfluor
ID: J72-Y2023
