Synthesis of Alkyl and Aryl Boronate Esters via CeO₂-Catalyzed Borylation of Alkyl and Aryl Electrophiles Including Alkyl Chlorides

Ramesh Bhawar, Suresh Saini, Kiran S. Patil, D. H. Nagaraju, Shubhankar Kumar Bose*

*Centre for Nano and Material Sciences (CNMS), JAIN (Deemed-to-be University), Jain Global Campus, Bangalore, 562112, India, Email: b.shubhankarjainuniversity.ac.in

R. Bhawar, S. Saini, K. S. Patil, D. H. Nagaraju, S. K. Bose, J. Org. Chem., 2023, 88, 16270-16279.

DOI: 10.1021/acs.joc.3c01755

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Abstract

CeO₂ nanorods catalyze the borylation of alkyl halides and aryl iodides with B₂pin₂. A wide range of synthetically useful boronate esters are readily obtained demonstrating broad utility and functional group tolerance. The catalyst can be reused for up to six runs without appreciable loss in activity.

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Key Words

alkylboronates, arylboronates

ID: J42-Y2023

Synthesis of Alkyl and Aryl Boronate Esters via CeO2-Catalyzed Borylation of Alkyl and Aryl Electrophiles Including Alkyl Chlorides

Ramesh Bhawar, Suresh Saini, Kiran S. Patil, D. H. Nagaraju, Shubhankar Kumar Bose*

Synthesis of Alkyl and Aryl Boronate Esters via CeO₂-Catalyzed Borylation of Alkyl and Aryl Electrophiles Including Alkyl Chlorides