Visible-Light-Driven Iron-Catalyzed Decarboxylative C-N Coupling Reaction of Alkyl Carboxylic Acids with NaNO₂

Shilei Yang, Yi Wang, Wenyao Xu, Xiao Tian, Ming Bao, Xiaoqiang Yu*

*Frontier Science Center for Smart Materials, Dalian University of Technology, Dalian, Liaoning 116023, People's Republic of China, Email: yuxiaoqiangdlut.edu.cn

S. Yang, Y. Wang, W. Xu, X. Tian, M. Bao, X. Yu, Org. Lett., 2023, 25, 8834-8838.

DOI: 10.1021/acs.orglett.3c03526

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Abstract

An efficient visible-light-driven iron-catalyzed decarboxylative C-N coupling reaction of alkyl carboxylic acids with NaNO₂ provides oximes in very good yields under mild, photosensitizer-free conditions. The reaction offers broad functional group tolerance and an easy operation.

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proposed mechanism

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Key Words

oximes, photochemistry

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ID: J54-Y2023