Visible-Light-Promoted Metal- and Photocatalyst-Free Reactions between Arylglyoxylic Acids and Tetraalkylthiuram Disulfides: Synthesis of α-Ketoamides
Subhankar Sarkar, Satyajit Pal, Anindita Mukherjee, Sougata Santra, Grigory V. Zyryanov, Adinath Majee*
*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India,
Email: adinath.majee
visva-bharati.ac.in
S. Sarkar, S. Pal, A. Mukherjee, S. Santra, G. V. Zyryanov, A. Majee, J. Org. Chem., 2024, 89, 1473-1482.
DOI: 10.1021/acs.joc.3c02081
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Abstract
Visible light mediates a convenient oxidative cross-coupling of arylglyoxylic acids with tetraalkylthiuram disulfides to provide α-ketoamides in good yields under ambient air at room temperature via a radical pathway.
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proposed mechanism
Key Words
ID: J42-Y2024
