Highly Enantioselective Hydrosilylation of Aromatic Alkenes
Jakob F. Jensen, Bo Y. Svendsen, Thomas V. la Cour, Henriette L. Pedersen and Mogens Johannsen*
*Department of Chemistry, Technical University of Denmark, Building 201,
DK-2800 Kgs Lyngby, Denmark, Email: mj
kemi.dtu.dk
J. F. Jensen, B. Y. Svendsen, T. V. la Cour, H. L. Pedersen, M. Johannsen, J. Am. Chem. Soc., 2002, 124, 4558-4559.
DOI: 10.1021/ja025617q
Abstract
A novel catalytic system for the asymmetric hydrosilylation of aromatic alkenes is described, which leads to silanes in high yields and with excellent enantioselectivity. The reaction works efficiently for a variety of substituted aromatic alkenes, giving access after Tamao oxidation to almost optically pure benzylic alcohols in high yields.
see article for more examples
Key Words
Benzylsilanes, Tamao Oxidation
ID: J48-Y2002-1100
