Application of the Fluorous Biphase Concept to Palladium-Catalyzed Suzuki Couplings
Siegfried Schneider, Willi Bannwarth*
*Universität Freiburg, Institut für Organische Chemie und Biochemie,
Albertstrasse 21, D-79104 Freiburg, Email: willi.bannwarth
organik.chemie.uni-freiburg.de
S. Schneider, W. Bannwarth, Helv. Chim. Acta, 2001, 84, 735-742.
DOI: 10.1002/1522-2675(20010321)84:3<735::AID-HLCA735>3.0.CO;2-L
Zusammenfassung:
Suzuki couplings were performed in high yields in a fluorous biphase system applying various perfluoro-tagged Pd complexes. The fluorous phase containing the catalyst could be reused six times without significant decrease in coupling yield.
see article for more examples
Fluorous Biphasic Catalysis without Perfluorinated Solvents: Application to Pd-Mediated Suzuki and Sonogashira Couplings
C. C. Tzschucke, C. Markert, H. Glatz, W. Bannwarth, Angew. Chem. Int. Ed., 2002, 41, 4500-4503.
DOI: 10.1002/1521-3773(20021202)41:23<4500::AID-ANIE4500>3.0.CO;2-N
Key Words
Suzuki Coupling, fluorous, biaryls
ID: J30-Y2001-060
