Palladium-Catalyzed Hydrophosphinylation of Alkenes and Alkynes

Sylvine Deprèle and Jean-Luc Montchamp*

*Department of Chemistry, Box 298860, Texas Christian University, Fort Worth, Texas 76129, Email: j.montchamptcu.edu

S. Deprele, J.-L. Montchamp, J. Am. Chem. Soc., 2002, 124, 9386-9387.

DOI: 10.1021/ja0261978

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Abstract

Various palladium catalysts promote the mild addition of hypophosphorous derivatives ROP(O)H₂ to alkenes and alkynes in good yields. With styrene and terminal alkynes, the regioselectivity (linear versus branched products) can be controlled to some extent with the catalytic system employed.

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AIBN-Initiated Radical Reactions of Ethyl Phosphinate

M. I. Antczak, J.-L. Montchamp, Synthesis, 2006, 3080-3084.

Triethylborane-Initiated Room Temperature Radical Addition of Hypophosphites to Olefins:  Synthesis of Monosubstituted Phosphinic Acids and Esters

S. Deprèle, J.-L. Montchamp, J. Org. Chem., 2001, 66, 6745-6755.

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Key Words

Phosphinic Acids

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ID: J48-Y2002-1240