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Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-3-ones

Guangxin Liang, Stefan N. Gradl and Dirk Trauner*

*Center for New Directions in Organic Synthesis, Department of Chemistry, University of California-Berkeley, Berkeley, California 94720, Email:

G. Liang, S. N. Gradl, D. Trauner, Org. Lett., 2003, 5, 4931-4934.

DOI: 10.1021/ol036019z


Expeditious and high-yielding Nazarov cyclizations of 2-alkoxy-1,4-pentadien-3-ones are described. An example of a catalytic asymmetric Nazarov cyclization is presented.

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Key Words

Nazarov Cyclization

ID: J54-Y2003-1280