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A Direct Catalytic Asymmetric Mannich-type Reaction to syn-Amino Alcohols

Barry M. Trost* and Lamont R. Terrell

*Department of Chemistry, Stanford University, Stanford, California 94305-5080, Email: bmtroststanford.edu

B. M. Trost, L. R. Terell, J. Am. Chem. Soc., 2003, 125, 338-339.

DOI: 10.1021/ja028782e



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Abstract

A dinuclear zinc catalyst was applied to a highly asymmetric Mannich-type reaction to generate syn 1,2-amino alcohols.

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Key Words

Amino Ketone Derivatives


ID: J48-Y2003-1290