Organic Chemistry Portal



A Direct Catalytic Asymmetric Mannich-type Reaction to syn-Amino Alcohols

Barry M. Trost* and Lamont R. Terrell

*Department of Chemistry, Stanford University, Stanford, California 94305-5080, Email:

B. M. Trost, L. R. Terell, J. Am. Chem. Soc., 2003, 125, 338-339.

DOI: 10.1021/ja028782e

see article for more reactions


A dinuclear zinc catalyst was applied to a highly asymmetric Mannich-type reaction to generate syn 1,2-amino alcohols.

see article for more examples

Key Words

Amino Ketone Derivatives

ID: J48-Y2003-1290