An Efficient Aerobic Oxidation of Alcohols to Aldehydes and Ketones with TEMPO/Ceric Ammonium Nitrate as Catalysts
Sung Soo Kim*, Hyun Chul Jung
*Department of Chemistry and Center for Chemical Dynamics, Inha University, Incheon 402-751, South Korea, Email: sungsooinha.ac.kr
S. S. Kim, H. C. Jung, Synthesis, 2003, 2135-2137.
The combination of TEMPO and CAN can be used for the aerobic oxidation of benzylic and allylic alcohols into their corresponding carbonyl compounds. However, steric hindrance has been observed to impede the reaction with some substituted allylic systems. The present method is superior to others currently available due to its relatively short reaction times and excellent yields.
see article for more examples
simplified oxidation mechanism
air oxidation, TEMPO, cerium ammonium nitrate, benzylic alcohols, allylic alcohols, aldehydes, ketones, enones