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An Easy and Convenient Synthesis of Weinreb Amides and Hydroxamates

Lidia De Luca, Giampaolo Giacomelli* and Maurizio Taddei

*Dipartimento di Chimica, Universita degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy, Email:

L. De Luca, G. Giacomelli, M. Taddei, J. Org. Chem., 2001, 66, 2534-2537.

DOI: 10.1021/jo015524b (free Supporting Information)


A convenient and simple one-flask method for the preparation of Weinreb amides, hydroxamates and hydroxamic acids even in large scale is described.

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Key Words

Hydroxamates, Weinreb Ketone Synthesis, activated ester

ID: J42-Y2001-110