A Convenient Method for the Synthesis of Terminal (E)-1,3-Dienes
Yong Wang, F. G. West*
*Department of Chemistry, 11227 Saskatchewan Drive, University of Alberta,
Edmonton, Alberta T6G 2G2, Canada, Email: frederick.west
ualberta.ca
Y. Wang, F. G. West, Synthesis, 2002, 99-103.
DOI: 10.1055/s-2002-19297
Abstract
Lithiated allylic phosphonates undergo efficient olefination reactions with a variety of aldehydes in the presence of HMPA to give terminal 1,3-dienes with high selectivity for the E-isomer. This method is general and procedurally simple.
see article for more examples
Key Words
aldehydes, alkenation, phosphorus, Wittig-Horner reaction, ylides
ID: J66-Y2002-1440
