One-pot Conversion of t-Butyl Carbamates to Amides with Acyl Halide-Methanol Mixtures
Abdesslame Nazih*, Denis Heissler
*Université Louis Pasteur et Centre National de la Recherche Scientifique,
Institut de Chimie, BP 296, 67008 Strasbourg, France, Email: nazih
chimie.u-strasbg.fr
A. Nazih, D. Heissler, Synthesis, 2002, 203-206.
DOI: 10.1055/s-2002-19803
Abstract
Acyl halide-methanol mixtures are efficient reagents for the one-pot transformation of t-butyl carbamates into amides. This transformation can be carried out in the presence of a benzyloxycarbonyl group.
see article for more examples
Key Words
tert-butyl carbamates, acylations, amides, chemoselectivity, protecting groups
ID: J66-Y2002-1450
