Iodine-Catalyzed, Efficient and Mild Procedure for Highly Chemoselective Acetalization of Carbonyl Compounds under Neutral Aprotic Conditions
Babak Karimi*, Behzad Golshani
*Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P.O.Box 45195-159, Gava Zang, Zanjan, Iran, Email: Karimiiasbs.ac.ir
B. Karimi, B. Golshani, Synthesis, 2002, 784-788.
Various types of carbonyl compounds are efficiently converted to their 1,3-dioxanes by the use of 1,3-bis(trimethylsiloxy)propane (BTSP) and a catalytic amount of iodine under essentially neutral aprotic condition.
see article for more examples
Efficient and Chemoselective Conversion of Carbonyl Compounds to 1,3-Dioxanes Catalyzed with N-Bromosuccinimide under Almost Neutral Reaction Conditions
B. Karimi, G. R. Ebrahimian, H. Seradj, Org. Lett., 1999, 1, 1737-1739.
carbonyl compounds, chemoselectivity, protection, 1,3-bis(trimethylsiloxy)propane, iodine, 1,3-dioxanes