Lithium Perchlorate Catalyzed Regioselective Ring Opening of Aziridines with Sodium Azide and Sodium Cyanide
Jhillu S. Yadav*, Basi V. Subba Reddy, G. Parimala, P. Venkatram Reddy
*Organic Chemistry Division-I, Indian Institute of Chemical Technology,
Hyderabad 500 007, India,
Email: yadavpub
iict.ap.nic.in
J. S. Yadav, B. V. S. Reddy, G. Parimala, P. Venkatram Reddy, Synthesis, 2002, 2383-2386.
DOI: 10.1055/s-2002-35222
Abstract
Aziridines react smoothly with sodium azide and sodium cyanide in the presence of a catalytic amount of lithium perchlorate under essentially mild and neutral reaction conditions to afford the corresponding β-azido and β-cyanoamines in high yields with high regioselectivity.
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Key Words
lithium perchlorate, aziridines, regioselective, β-azidoamines, β-aminonitriles
ID: J66-Y2002-1670
