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Bidentate Ligands by Self-Assembly through Hydrogen Bonding: A General Room Temperature/Ambient Pressure Regioselective Hydroformylation of Terminal Alkenes

Wolfgang Seiche, Alexander Schuschkowski, Bernhard Breit*

*Institut für Organische Chemie und Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, 79104 Freiburg, Germany, Email:

W. Seiche, A. Schuschkowski, B. Breit, Adv. Syn. Catal., 2005, 1488-1494.

DOI: 10.1002/adsc.200505174


The 6-DPPon/rhodium catalyst allows for the first time a room temperature/ambient pressure hydroformylation of various, structurally diverse terminal alkenes with low catalyst loadings. This protocol omits the need for special pressure equipment and should find wide application in organic synthesis.

Key Words

Hydroformylation, Carbonyl Compounds

ID: JXX-Y2005-2760