Synthesis of Allenes via Palladium-Catalyzed Hydrogen-Transfer Reactions: Propargylic Amines as an Allenyl Anion Equivalent

Hiroyuki Nakamura,* Takaya Kamakura, Makoto Ishikura and Jean-François Biellmann

*Department of Chemistry, Faculty of Science, Gakushuin University, Mejiro, Toshima-ku, Tokyo 171-8588, Japan, Email: hiroyuki.nakamuragakushuin.ac.jp

H. Nakamura, T. Kamakura, M. Ishikura, J.-F. Biellmann, J. Am. Chem. Soc., 2004, 126, 5958-5959.

DOI: 10.1021/ja039175+

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Abstract

Various propargylic amines underwent a palladium-catalyzed hydrogen-transfer reaction in the presence of (C₆F₅)₃P, giving the corresponding allenes in good yields.

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Key Words

Allenes, Propargylic Alcohols, Sonogashira Coupling

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ID: J48-Y2004-1480