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Organic Reactions in Ionic Liquids: Knoevenagel Condensation Catalyzed by Ethylenediammonium Diacetate

Ce Su, Zhen-Chu Chen*, Qin-Guo Zheng

*Department of Chemistry, Zhejiang University (Xi-xi campus), Hangzhou, 310028, P. R. China, Email:

C. Su, Z.-C. Chen, Q.-G. Zhen, Synthesis, 2003, 555-559.

DOI: 10.1055/s-2003-37643


The ionic liquid 1-butyl-3-methylimidazonium tetrafluoroborate [bmim]BF4 was used for ethylenediammonium diacetate (EDDA)-catalyzed Knoevenagel condensation between aldehydes or ketones with active methylene compounds. Catalyst and solvent can be recycled.

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Key Words

Ionic liquids, Green Chemistry, Catalysis, Knoevenagel Condensation, Carbonyl Compounds, Coumarins

ID: J66-Y2003-1790