Triphenylphosphine Catalyzed Michael Addition of Oximes onto Activated Olefins
Debnath Bhuniya*, Sankar Mohan, Sanju Narayanan
*Metabolic Disorder (Chemistry) Group, DiscoveryResearch SBU, Dr. Reddy’s LaboratoriesLimited, Miyapur, Bollaram Road, Hyderabad 500050, India, Email: debnathbhuniyadrreddys.com
D. Bhuniya, S. Mohan, S. Narayanan, Synthesis, 2003, 1018-1024.
A new reaction condition for Michael addition of oximes onto activated olefins has been discovered using a catalytic amount of triphenylphosphine. Various aldoximes and ketoximes were reacted with different Michael acceptors in good yields.
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Michael additions, oximes, alkenes, phosphorus, catalysis