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Efficient Addition of Allylsilanes to α,β-Enones Using Catalytic Indium and Trimethylsilyl Chloride

Phil Ho Lee*, Dong Seomoon, Sundae Kim, K. Nagaiah, S. V. Damle, Kooyeon Lee

*Department of Chemistry, Kangwon National University, Chunchon 200-701, Republic of Korea, Email:

P. H. Lee, D. Seomoon, S. Kim, K. Nagaiah, S. V. Damle, K. Lee, Synthesis, 2003, 2023-2026.

DOI: 10.1055/s-2003-41017


α,β-Enones undergo an efficient Hosomi-Sakurai reaction with allyltrimethylsilane, in which a catalytic amount of indium is used in the presence of trimethylsilyl chloride as an activator under mild conditions to produce the conjugate addition products in good yields.

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Key Words

addition reactions, allylation, catalysis, indium, Hosomi-Sakurai reaction, Michael addition, ketones, silicon

ID: J66-Y2003-2000