Mild and Efficient Hydrolysis of Aromatic Thioacetals/Thioketals using o-Iodoxybenzoic acid (IBX) in Presence of β- Cyclodextrin in Water
N. Srilakshmi Krishnaveni, K. Surendra, Y. V. D. Nageswar, K. Rama Rao*
*Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India, Email: ramaraokiict.res.in
N. S. Krishnaveni, K. Surendra, Y. V. D. Nageswar, K. R. Rao, Synthesis, 2003, 2295-2297.
An efficient and convenient procedure has been developed for the hydrolysis of thioacetals/thioketals to the corresponding carbonyl compounds in excellent yields with o-iodoxybenzoic acid (IBX) in presence of β-cyclodextrin (β-CD) in water under neutral conditions at room temperature.
see article for more examples
Deoximation of Oximes with 2-Iodylbenzoic Acid in Water in the Presence of β-Cyclodextrin
N. S. Krishnaveni, K. Surendra, Y. V. D. Nageswar, K. R. Rao, Synthesis, 2003, 1968-1969.
hydrolysis (thioacetals, thioketals, 1,3-dithianes, 1,3-dithiolanes) o-iodoxybenzoic acid, β-cyclodextrin, water, green chemistry