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One-Pot Synthesis of 3-Substituted Isoxazoles from Phenyl Vinylic Selenide

Shou-Ri Sheng*, Xiao-Ling Liu, Qu Xu, Cai-Sheng Song

*Department of Chemistry, Jiangxi Normal University, Nanchang, 330027, P. R. China, Email:

S.-R. Sheng, X.-L. Liu, Q. Xu, C.-S. Song, Synthesis, 2003, 2763-2764.

DOI: 10.1055/s-2003-44354


A 1,3-dipolar cycloaddition of phenyl vinylic selenide to nitrile oxides and subsequent oxidation-elimination furnished 3-substituted isoxazoles with good yields in a one-pot, two-step transformation.

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Key Words

isoxazoles, phenyl vinylic selenide, 1,3-dipolar cycloaddition, oxidation-elimination

ID: J66-Y2003-2120