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Efficient Conversion of Carboxylic Acids into N-Acylbenzotriazoles

Alan R. Katritzky*, Yuming Zhang, Sandeep K. Singh

*Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA, Email: Katritzkychem.ufl.edu

A. R. Katritzky, N. Kirichenko, B. V. Rogovoy, Synthesis, 2003, 2777-2780.

DOI: 10.1055/s-2003-42462


Abstract

An improved one-pot procedure for the preparation of N-acylbenzotriazoles involves mild reaction conditions and allows the preparation of several derivatives not accessible by the previously reported methods.

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Key Words

N-acylbenzotriazole, carboxylic acid, benzotriazole, thionyl chloride, acylation reagent


ID: J66-Y2003-2140