Efficient Conversion of Carboxylic Acids into N-Acylbenzotriazoles
Alan R. Katritzky*, Yuming Zhang, Sandeep K. Singh
*Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA, Email: Katritzkychem.ufl.edu
A. R. Katritzky, N. Kirichenko, B. V. Rogovoy, Synthesis, 2003, 2777-2780.
An improved one-pot procedure for the preparation of N-acylbenzotriazoles involves mild reaction conditions and allows the preparation of several derivatives not accessible by the previously reported methods.
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N-acylbenzotriazole, carboxylic acid, benzotriazole, thionyl chloride, acylation reagent