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Direct Access to Ketones from Aldehydes via Rhodium-Catalyzed Cross-Coupling Reaction with Potassium Trifluoro(organo)borates

Mathieu Pucheault, Sylvain Darses* and Jean-Pierre Genet*

*Laboratoire de Synthèse Sélective Organique (UMR 7573, CNRS), Ecole Nationale Supérieure de Chimie de Paris, 11 rue P&M Curie, 75231 Paris Cedex 05, France, Email: darsesext.jussieu.fr, genetext.jussieu.fr

M. Pucheault, S. Darses, J-P. Genet, J. Am. Chem. Soc., 2004, 126, 15356-15357.

DOI: 10.1021/ja044749b (free Supporting Information)


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Abstract

A direct cross-coupling reaction of aromatic aldehydes with potassium trifluoro(organo)borates afforded ketones in high yields and under mild conditions in the presence of a rhodium catalyst and acetone.

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Key Words

Arylketones


ID: J48-Y2004-1850