Conversion of Benzal Halides to Benzaldehydes in the Presence of Aqueous Dimethylamine
*Bayer Pharmaceuticals Corporation, Department of Chemistry Research, West Haven, CT 06516, USA, Email: donald.bankston.bbayer.com
D. Bankston, Synthesis, 2004, 283-289.
Aqueous dimethylamine is an efficient reagent for the conversion of various benzal halides to their corresponding benzaldehydes. The method represents a novel, economical approach to acquire pure, substituted benzaldehydes from commercially available, or easily prepared starting materials.
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aqueous dimethylamine, benzal halides, hydrolysis, benzaldehydes, N,N-dimethylformamide