Highly Efficient Regioselective Ring Opening of Aziridines to β-Haloamines in the Presence of β-Cyclodextrin in Water
N. Srilakshmi Krishnaveni, K. Surendra, M. Narender, Y. V. D. Nageswar, K. Rama Rao*
*Organic Chemistry Division-I, Indian Institute of Chemical Technology,
Hyderabad-500 007, India, Email: ramaraok
iict.res.in
N. S. Krishnaveni, K. Surendra, M. Narender, Y. V. D. Nageswar, K. R. Rao, Synthesis, 2004, 501-502.
DOI: 10.1055/s-2004-815946
Abstract
Aziridines are opened regioselectively with hydrogen and lithium halides to yield β-haloamines in the presence of β-cyclodextrin using water as the solvent.
see article for more examples
M. Arjun Reddy, K. Surendra, N. Bhanumathi, K. Rama Rao, Tetrahedron, 2002, 58, 6003-6008.
Key Words
aziridines, hydrogen halides, lithium halides, β-cyclodextrin, water, green chemistry, 1,2-chloroamines, 1,2-bromoamines, 1,2-iodoamines
ID: J66-Y2004-1980
