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A Simple and Facile Carboxylation Method and Its Application for Synthesis of Liquid Crystals

Adam Shih-Yuan Lee*, Chih-Chiang Wu, Li-Shin Lin, Hsiu-Fu Hsu

*Department of Chemistry, Tamkang University, Tamsui, Taiwan, Email:

A. S.-Y. Lee, C.-C. Wu, L.-S. Lin, H.-F. Hsu, Synthesis, 2004, 568-572.

DOI: 10.1055/s-2004-815944


Sonication of a mixture of magnesium powder, 1,2-dibromoethane, aryl bromide and diethyl dicarbonate in THF followed by treatment with BF3ˇOEt2 at room temperature afforded aryl ester with reasonable yield. A series of aryl bromides were investigated and transformed to their corresponding aryl esters.

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Key Words

carboxylation, Barbier reaction, diethyl dicarbonate, Lewis acid, liquid crystal, sonochemistry

ID: J66-Y2004-1990