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Efficient and Mild Ytterbium(III)-Catalyzed Tosylation of Alcohols

Slobodan Comagic, Ralf Schirrmacher*

*Institute of Nuclear Chemistry, University of Mainz , Fritz Strassmann-Weg 2, 55128 Mainz, Germany, Email:

S. Comagic, R. Schirrmacher, Synthesis, 2004, 885-888.

DOI: 10.1055/s-2004-815998


Ytterbium(III) trifluoromethanesulfonate efficiently catalyzes the reaction of primary and secondary alcohols with toluenesulfonic acid anhydride to yield the alkyl tosylates in high yields. The reactions were carried out under neutral and mild conditions and product purification was easily achieved by means of short column chromatography.

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Key Words

ytterbium(III) trifluoromethanesulfonate, alcohols, catalysis, tosylation, Lewis acids

ID: J66-Y2004-2040