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Activated Carbon-Promoted Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines and 1,3,5-Trisubstituted Pyrazolines Using Molecular Oxygen

Natsuki Nakamichi, Yuka Kawashita, Masahiko Hayashi*

*Department of Chemistry, Faculty of Science, Kobe University, Kobe 657-8501, Japan, Email: mhayashikobe-u.ac.jp

N. Nakamichi, Y. Kawashita, M. Hayashi, Synthesis, 2004, 1015-1020.

DOI: 10.1055/s-2004-822343


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Abstract

In the presence of activated carbon, Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolines were aromatized with molecular oxygen to the corresponding pyridines and pyrazoles in excellent yields.

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Key Words

activated carbon, aromatization, oxygen, oxidations, pyridines, pyrazoles, heterocycles


ID: J66-Y2004-2050