Safe radical azidonation using polystyrene supported diazidoiodate(I)
Lavinia Georgeta Marinescu, Christian Marcus Pedersen and Mikael Bols*
*Department of Chemistry, Aarhus University, Langelandsgade 140, 8000
DK-Aarhus, Denmark, Email: bols
kemi.ku.dk
L. G. Marinescu, C. M. Pedersen, M. Bols, Tetrahedron, 2005, 61, 123-127.
DOI: 10.1016/j.tet.2004.10.040
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Abstract
Aldehydes are safely and conveniently converted to acyl azides and benzyl ethers to azido ethers by treatment with polymer supported iodine azide in MeCN at 83 °C. The reaction provides an alternative to the use of iodine azide in radical azidonations.
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Radical Azidonation of Aldehydes
L. Marinescu, J. Thinggaard, I. B. Thomsen, M. Bols, J. Org. Chem., 2003, 68, 9453-9455.
Key Words
carbamoyl azides, 1,2-azido ethers, Curtius Rearrangement
ID: J72-Y2005-2770
