Cobalt(II)-catalyzed direct acetylation of alcohols with acetic acid
Subbarayan Velusamy, Sarbani Borpuzari and T. Punniyamurthy
*Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India, Email: tpunniiitg.ernet.in
S. Velusamy, S. Borpuzari, T. Punniyamurthy, Tetrahedron, 2005, 61, 2011-2015.
Cobalt(II) chloride hexahydrate efficiently catalyzes the acetylation of alcohols with AcOH in high yields without the need to remove water. This protocol is also effective with other carboxylic acids. The catalyst can be recycled.
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Esterification, Acetylation, Alcohol, Carboxylic acid, Cobalt(II) chloride, Catalyst