Highly chemoselective hydrogenation method using novel finely dispersed palladium catalyst on silk-fibroin: its preparation and activity
Takashi Ikawa, Hironao Sajiki* and Kosaku Hirota
*Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, 5-6-1
Mitahora-higashi, Gifu 502-8585, Japan, Email: sajiki
gifu-pu.ac.jp
T. Ikawa, H. Sajiki, K. Hirota, Tetrahedron, 2005, 61, 2217-2231.
DOI: 10.1016/j.tet.2004.11.080
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Abstract
A palladium-fibroin complex catalyzed the chemoselective hydrogenation of acetylenes, olefins and azides in the presence of aromatic ketones and aldehydes, halides, N-Cbz protective groups and benzyl esters which are readily hydrogenated using Pd/C or Pd/C(en) as a catalyst.
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Pd/C-Catalyzed Chemoselective Hydrogenation in the Presence of Diphenylsulfide
A. Mori, Y. Miyakawa, E. Ohashi, T. Haga, T. Maegawa, H. Sajiki, Org. Lett., 2006, 8, 3279-3281.
Key Words
Silk-fibroin, Hydrogenation, Palladium catalyst, Chemoselective, Hydrogen
ID: J72-Y2005-2850
