Room temperature ionic liquid promoted improved and rapid synthesis of 2,4,5-triaryl imidazoles from aryl aldehydes and 1,2-diketones or α-hydroxyketone
Shapi A. Siddiqui, Umesh C. Narkhede, Sanjay S. Palimkar, Thomas Daniel, Rajgopal J. Lahoti and Kumar V. Srinivasan*
*Division of Organic Chemistry; Technology, National Chemical Laboratory,
Dr. Homi Bhabha Road, Pune 411 008, India, Email: kvsri
dalton.ncl.res.in
S. A. Siddiqui, U. C. Narkhede, S. S. Palimkar, T. Daniel, R. J. Lahoti, K. V. Srinivasan, Tetrahedron, 2005, 61, 3539-3546.
DOI: 10.1016/j.tet.2005.01.116
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Abstract
An improved and rapid one-pot synthesis of 2,4,5-triaryl imidazoles in a room temperature ionic liquid does not need any added catalyst. This one-pot methodology offers excellent isolated yields, simple work up procedures and efficient recovery and recycling of the ionic liquid.
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Key Words
imidazoles, ionic liquids, ammonium acetate, benzaldehydes, 1,2-diketones, α-hydroxyketones
ID: J72-Y2005-2890
