A New Convenient Preparation of Thiol Esters Utilizing N-Acylbenzotriazoles
Alan R. Katritzky*, Aleksandr A. Shestopalov, Kazuyuki Suzuki
*Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA, Email: katritzkychem.ufl.edu
A. R. Katritzky, A. A. Shestopalov, K. Suzuki, Synthesis, 2004, 1806-1813.
Diverse thiol esters were synthesized in good yields by reactions of thiophenol, benzyl mercaptan, ethyl mercaptoacetate, and mercaptoacetic acid with N-acylbenzotriazoles under mild conditions. These results demonstrate the utility of N-acylbenzotriazoles as mild S-acylating agents.
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