Domino Primary Alcohol Oxidation-Wittig Reaction: Total Synthesis of ABT-418 and (E)-4-Oxonon-2-enoic Acid
Jyoti Shet, Vidya Desai, Santosh Tilve*
*Department of Chemistry, Goa University, Taleigao Plateau, Goa 403 206,
India, Email: santoshtilve
yahoo.com
J. Shet, V. Desai, S. Tilve, Synthesis, 2004, 1859-1863.
DOI: 10.1055/s-2004-829123
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Abstract
A domino oxidation of primary alcohols gives α,β-unsaturated compounds using the combination of PCC-NaOAc and stabilized Wittig reagents.
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Key Words
primary alcohols, oxidation, pyridinium chlorochromate, olefination, enones, α,β-unsaturated esters, domino reaction
ID: J66-Y2004-2240
