Organic Chemistry Portal



Nonmetal-Catalyzed Iodination of Arenes with Iodide and Hydrogen Peroxide

Jernej Iskra*, Stojan Stavber, Marko Zupan

*Laboratory for Organic and Bioorganic Chemistry, Jozef Stefan Institute and Faculty of Chemistry and Chemical Technology, University of Ljubljana, Jamova 39, 1000 Ljubljana, Slovenia, Email:

J. Iskra, S. Stavber, M. Zupan, Synthesis, 2004, 1869-1873.

DOI: 10.1055/s-2004-829136


A selective and efficient oxidative iodination of electron rich arenes was carried out with one equivalent of KI and two equivalents of 30% hydrogen peroxide in MeOH in the presence of strong acid.

see article for more examples

Key Words

iodination, haloperoxidation, hydrogen peroxide, oxidative halogenation, aromatics

ID: J66-Y2004-2250