Organic Chemistry Portal



Ferric(III) Chloride-Promoted Efficient Thiocyanation of Arylalkenes: A Facile Synthesis of Dithiocyanates

J. S. Yadav*, B. V. S. Reddy, Manoj Kumar Gupta

*Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500007, India, Email:

J. S. Yadav, B. V. S. Reddy, M. K. Gupta, Synthesis, 2004, 1983-1986.

DOI: 10.1055/s-2004-829150


Anhydrous FeCl3 oxidizes potassium thiocyanate to the corresponding radical and promotes subsequent addition to nucleophilic olefins to produce dithiocyanate derivatives under mild conditions with excellent yields and chemoselectivities. The use of ferric chloride makes this method simple, convenient and practical.

see article for more examples

Iron(III) Chloride as Mild and Efficient Reagent for the α-Thiocyanation of Ketones: An Expedient Synthesis of α-Oxo Thiocyanates

J. S. Yadav, B. V. S. Reddy, U. V. S. Reddy, D. N. Chary, Synthesis, 2008, 1283-1287.

Key Words

oxidative radical addition, alkenes, dithiocyanates, ferric chloride

ID: J66-Y2004-2270