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Application of recoverable nanosized palladium(0) catalyst in Sonogashira reaction

Pinhua Li, Lei Wang*, Hongji Li

*Department of Chemistry, Huaibei Coal Teachers College, Huaibei, Anhui 235000, People's Republic of China, Email:

P. Li, L. Wang, H. Li, Tetrahedron, 2005, 61, 8633-8640.

DOI: 10.1016/j.tet.2005.07.013


Poly(vinylpyrrolidone) (PVP) supported nanosized palladium metal colloids catalyzed the Sonogashira reaction of aryl iodides and bromides with terminal alkynes in the absence of ligand, copper and amine in an environmental-friendly reaction system with ethanol as the solvent and potassium carbonate as a base. The catalyst can be recovered and recycled by a simple decantation.

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Key Words

Nanoparticle palladium metal, Sonogashira coupling, Ligand free, Copper free, Amine free

ID: J72-Y2005-3040