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Silver Phosphotungstate: A Novel and Recyclable Heteropoly Acid for Friedlšnder Quinoline Synthesis

J. S. Yadav*, B. V. S. Reddy, P. Sreedhar, R. Srinivasa Rao, K. Nagaiah

*Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500 007, India, Email:

J. S. Yadav, B. V. S. Reddy, P. Sreedhar, R. S. Rao, K. Nagaiah, Synthesis, 2004, 2381-2385.

DOI: 10.1055/s-2004-831185


o-Aminoaryl ketones undergo a smooth, mild and selective condensation with α-methylene ketones on the surface of silver heteropoly acid (Ag3PW12O40) to afford the corresponding polysubstituted quinolines in excellent yields. The catalyst can be recovered by simple filtration and can be recycled.

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Key Words

heteropoly acids, o-aminoaryl ketones, α-methylene ketones, quinolines, Friedlšnder synthesis

ID: J66-Y2004-2350