IBX/n-Bu4NBr/CH2Cl2-H2O: a new mild system for selective oxidation of secondary alcohols
Chutima Kuhakarn*, Krisada Kittigowittana, Manat Pohmakotr and Vichai Reutrakul
*Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand, Email: scckkmahidol.ac.th
C. Kuhakarn, K. Kittigowittana, M. Pohmakotr, V. Reutrakul, Tetrahedron, 2005, 61, 8995-9000.
A chemoselective oxidation of secondary alcohols with IBX/n-Bu4NBr in CH2Cl2-H2O gave ketones in good yields and allowed the oxidation of secondary hydroxyl group even in the presence of primary hydroxyl groups.
see article for more examples
Selective oxidation, Ketones, IBX oxidation