Use of tetrahydropyrimidinium salts for highly efficient palladium-catalyzed cross-coupling reactions of aryl bromides and chlorides
Ismail Özdemir*, Serpil Demir and Bekir Çetinkaya
*Department of Chemistry, Inönü Universityt, 44280 Malatya, Turkey, Email:
iozdemir
inonu.edu.tr
I. Özdemir, S. Demir, B. Çetinkaya, Tetrahedron, 2005, 61, 9791-9798.
DOI: 10.1016/j.tet.2005.06.064
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Abstract
Sterically demanding 1,3-dialkyl-3,4,5,6-tetrahydropyrimidinium salts as NHC precursors in combination with palladium acetate provided active catalysts for the cross-coupling of aryl chlorides and bromides under mild conditions. The catalytic system was applied to the Heck, Suzuki and benzaldehyde coupling reactions.
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Key Words
Suzuki Coupling, Heck Reaction, Biaryl Synthesis
ID: J72-Y2005-3090
