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1,3-Dibromo-5,5-Dimethylhydantoin [DBDMH] as an Efficient and Selective Agent for the Oxidation of Thiols to Disulfides in Solution or under Solvent-Free Conditions

Ardeshir Khazaei*, Mohammad Ali Zolfigol, Amin Rostami

*Department of Chemistry, Faculty of Science, Bu-Ali Sina University, P.O. Box 65174-4119, Hamedan, Iran, Email:

A. Khazaei, M. A. Zolfigol, A. Rostami, Synthesis, 2004, 2959-2961.

DOI: 10.1055/s-2004-834919

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A mild and efficient oxidation of various thiols affords the corresponding disulfides using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) as oxidant under both solution and solvent-free conditions.

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Key Words

1,3-dibromo-5,5-dimethylhydantoin, oxidation, thiols, disulfides

ID: J66-Y2004-2410