An Efficient Preparation of 2-Imidazolines and Imidazoles from Aldehydes with Molecular Iodine and (Diacetoxyiodo)benzene
Midori Ishihara, Hideo Togo*
*Graduate School of Science and Technology, Chiba University, Yayoi-cho
1-33, Inage-ku, Chiba 263-8522, Japan, Email: togo
faculty.chiba-u.jp
M. Ishihara, H. Togo, Synlett, 2006, 227-230.
DOI: 10.1055/s-2005-923604
Abstract
2-Imidazolines were easily prepared in good yields from the reaction of aldehydes and ethylenediamine with iodine in the presence of potassium carbonate. The 2-imidazolines were smoothly oxidized to the corresponding imidazoles in good yields using (diacetoxyiodo)benzene at room temperature.
see article for more examples
Facile Preparation of 2-Imidazolines from Aldehydes with tert-Butyl Hypochlorite
M. Ishihara, H. Togo, Synthesis, 2007, 1939-1942.
Key Words
2-imidazolines, imidazoles, iodine, iodosobenzene diacetate, aldehyde, ethylenediamine
ID: J60-Y2006-4200
