A Mild and Efficient Desilylation of O-tert-Butyldimethylsilyl Ethers Mediated by Chlorotrimethylsilane and Potassium Fluoride Dihydrate in Acetonitrile
Yu Peng, Wei-Dong Z. Li*
*State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
Lanzhou 730000, P. R. of China, Email: isoclzu.edu.cn
Y. Peng, W.-D. Z. Li, Synlett, 2006, 1165-1168.
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Abstract
A chemoselective, efficient and operationally simple desilylation of O-tert-butyldimethylsilyl ethers was achieved using chlorotrimethylsilane and potassium fluoride dihydrate in acetonitrile.
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Key Words
desilylation, potassium fluoride, chlorotrimethylsilane, O-tert-butyldimethylsilyl ether
ID: J60-Y2006-4370